Different FOXA1 classes drive prostate cancer
نویسندگان
چکیده
منابع مشابه
Androgen receptor-independent function of FoxA1 in prostate cancer metastasis.
FoxA1 (FOXA1) is a pioneering transcription factor of the androgen receptor (AR) that is indispensible for the lineage-specific gene expression of the prostate. To date, there have been conflicting reports on the role of FoxA1 in prostate cancer progression and prognosis. With recent discoveries of recurrent FoxA1 mutations in human prostate tumors, comprehensive understanding of FoxA1 function...
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ژورنال
عنوان ژورنال: Nature Reviews Urology
سال: 2019
ISSN: 1759-4812,1759-4820
DOI: 10.1038/s41585-019-0223-1